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Acrodermatitis Enteropathica

Also indexed as: Acrodermatitis Enteropathy, Zinc Malabsorption (Inherited)

Acrodermatitis enteropathica is a rare inherited disorder that results in the inability to absorb adequate amounts of zinc from the diet. Anyone who is severely zinc deficient can develop the symptoms of the inherited form of this disorder.

Checklist for Acrodermatitis Enteropathica

Rating Nutritional Supplements Herbs
3Stars Zinc  
3Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star An herb is primarily supported by traditional use, or the herb or supplement has little scientific support and/or minimal health benefit.

What are the symptoms of acrodermatitis enteropathica? Symptoms of this condition include growth retardation, diarrhea, hair loss, and a red skin rash. Skin around the fingernails may be red and swollen.

How is it treated? Doctors prescribe zinc supplements for people with acrodermatitis.

Dietary changes that may be helpful: Oysters, beef, liver, pumpkin seeds, pecans, and Brazil nuts are all high in zinc.1 However, people with acrodermatitis enteropathica also need to take zinc supplements.

Nutritional supplements that may be helpful: Supplementation with zinc brings about complete remission in hereditary acrodermatitis enteropathica. Zinc supplements in the amount of 30 to 150 mg per day are used by people with this condition.2 People with acrodermatitis enteropathica need to be monitored by a healthcare professional to ensure that their level of zinc supplementation is adequate and that the zinc supplements are not inducing a copper deficiency.

Are there any side effects or interactions? Refer to the individual supplement for information about any side effects or interactions.

References:

1. Murray MT. The Healing Power of Foods. Rocklin, CA: Prima Publishing, 1993, 7.

2. Berkow R. Merck Manual. Whitehouse Station, NJ: Merck Research Laboratories, 1987, 946.