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Propoxyphene

Also indexed as: Darvon®, Darvon®-N

Combination drugs: Coalgesic®, Co-Proxamol, Darvocet® N, Darvon® Compound, Distalgesic®, Propacet 100®, Wygesic®

Propoxyphene is a narcotic analgesic used to relieve mild to moderate pain. Propoxyphene is available alone and in combination with other drugs.

Safetychecker Summary for Propoxyphene
(for details about the summarized interactions, read the full article)

Check Check: Other—Before taking any of these supplements or eating any of these foods with your medication, read this article in full for details.

Fiber

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Food
Propoxyphene may cause gastrointestinal (GI) upset. Propoxyphene-containing products may be taken with food to reduce or prevent GI upset.1 A common side effect of narcotic analgesics is constipation.2 Increasing dietary fiber (especially vegetables and whole-grain foods) and water intake can ease constipation.

Alcohol
Propoxyphene may cause drowsiness, dizziness, or blurred vision. Alcohol may intensify these effects and increase the risk of accidental injury.3 To prevent problems, people taking propoxyphene should avoid alcohol.

References:

1. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

2. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

3. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.